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Gary E Shull Selected Research

Chloride-Bicarbonate Antiporters

1/2017RNA SEQ Analysis Indicates that the AE3 Cl-/HCO3- Exchanger Contributes to Active Transport-Mediated CO2 Disposal in Heart.
8/2014Critical role of bicarbonate and bicarbonate transporters in cardiac function.
1/2011Loss of the AE3 anion exchanger in a hypertrophic cardiomyopathy model causes rapid decompensation and heart failure.
9/2007Blindness caused by deficiency in AE3 chloride/bicarbonate exchanger.
4/2007PAT-1 (Slc26a6) is the predominant apical membrane Cl-/HCO3- exchanger in the upper villous epithelium of the murine duodenum.

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Gary E Shull Research Topics

Disease

5Acidosis
01/2022 - 12/2004
5Heart Failure
01/2017 - 03/2004
4Infarction (Infarctions)
11/2018 - 12/2005
4Ischemia
09/2007 - 10/2003
3Hypertension (High Blood Pressure)
11/2015 - 05/2010
3Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy)
12/2014 - 01/2011
3Cardiomegaly (Heart Hypertrophy)
12/2013 - 02/2005
3Neoplasms (Cancer)
09/2007 - 08/2005
2Insulin Resistance
10/2016 - 12/2013
2Darier Disease (Darier's Disease)
01/2015 - 10/2005
2Hypertrophy
12/2014 - 04/2009
2Reperfusion Injury
12/2013 - 10/2003
2Alkalosis
08/2012 - 09/2004
2Brain Ischemia (Cerebral Ischemia)
09/2007 - 01/2005
2Inflammation (Inflammations)
08/2005 - 12/2002
2Achlorhydria (Hypochlorhydria)
08/2005 - 04/2005
2Gitelman Syndrome
05/2005 - 09/2004
1Type 2 Diabetes Mellitus (MODY)
01/2021
1Stroke (Strokes)
11/2018
1Demyelinating Diseases (Demyelinating Disease)
11/2018
1Ischemic Stroke
01/2018
1Gliosis
01/2018
1Anemia
01/2016
1Atherosclerosis
07/2015
1Non-alcoholic Fatty Liver Disease
07/2014
1Wounds and Injuries (Trauma)
11/2013
1Kufor-Rakeb syndrome
05/2013
1Neuronal Ceroid-Lipofuscinoses (Neuronal Ceroid Lipofuscinosis)
05/2013
1Synucleinopathies
05/2013
1Osteopetrosis
02/2013
1Bone Resorption
02/2013
1Edema (Dropsy)
08/2012
1Renal Insufficiency (Renal Failure)
08/2012
1Hypokalemia
08/2012
1Nephrotic Syndrome (Syndrome, Nephrotic)
08/2012
1Cysts
01/2011
1Cystic Fibrosis (Mucoviscidosis)
04/2009
1Dehydration (Water Stress)
04/2009
1Benign Familial Pemphigus (Hailey Hailey Disease)
09/2007
1Blindness (Hysterical Blindness)
09/2007
1Adenoma (Adenomas)
04/2007
1Mitochondrial Diseases (Mitochondrial Disease)
03/2007
1Hypoxia (Hypoxemia)
03/2007
1Hypotension (Low Blood Pressure)
02/2006

Drug/Important Bio-Agent (IBA)

14Protein Isoforms (Isoforms)IBA
01/2022 - 02/2002
8Proteins (Proteins, Gene)FDA Link
01/2022 - 09/2004
7Adenosine Triphosphatases (ATPase)IBA
01/2015 - 03/2004
6AcidsIBA
01/2022 - 10/2002
5Chloride-Bicarbonate AntiportersIBA
01/2017 - 04/2007
4Sodium-Hydrogen ExchangersIBA
07/2014 - 12/2002
4AnionsIBA
02/2013 - 03/2007
3AmmoniaIBA
01/2022 - 08/2005
3SymportersIBA
07/2015 - 09/2004
3CalciumIBA
11/2013 - 03/2004
2Bicarbonates (Hydrogen Carbonate)IBA
01/2022 - 12/2004
2Glucose (Dextrose)FDA LinkGeneric
01/2021 - 10/2016
2Angiotensin IIIBA
11/2015 - 10/2015
2Sodium-Hydrogen Exchanger 3IBA
11/2015 - 10/2015
2LipidsIBA
07/2014 - 01/2011
2Messenger RNA (mRNA)IBA
06/2010 - 12/2002
2AldosteroneIBA
02/2006 - 09/2004
2ThiazidesIBA
05/2005 - 09/2004
2Plasma Membrane Calcium-Transporting ATPasesIBA
02/2005 - 02/2002
1EnzymesIBA
01/2022
1Sodium-Bicarbonate SymportersIBA
01/2021
1TamoxifenFDA LinkGeneric
11/2018
1Corn Oil (Oil, Corn)IBA
11/2018
1Interleukin-10 (Interleukin 10)IBA
11/2018
1Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA
11/2018
1IronIBA
01/2016
1Losartan (Cozaar)FDA LinkGeneric
10/2015
1Apolipoproteins E (ApoE)IBA
07/2015
1ApolipoproteinsIBA
07/2015
1Interleukin-18 (Interleukin 18)IBA
07/2015
1Interleukin-18 ReceptorsIBA
07/2015
1Mutant Proteins (Protein, Mutant)IBA
12/2014
1Crystallins (Crystallin)IBA
12/2013
1LipofuscinIBA
05/2013
1P-type ATPasesIBA
05/2013
1SynucleinsIBA
05/2013
1SaltsIBA
08/2012
1DiureticsIBA
08/2012
1Member 3 Solute Carrier Family 12IBA
08/2012
1TropomyosinIBA
01/2011
1Adrenergic Agents (Adrenergic Drugs)IBA
01/2011
1SodiumIBA
05/2010
1Phenylephrine (Neo-Synephrine)FDA LinkGeneric
04/2009
1Cystic Fibrosis Transmembrane Conductance Regulator (Protein, CFTR)IBA
04/2009
1CalcineurinIBA
04/2009
1Phosphotransferases (Kinase)IBA
09/2007
190-kDa Ribosomal Protein S6 Kinases (Ribosomal Protein S6 Kinases, 90 kDa)IBA
09/2007
1Bumetanide (Bumex)FDA LinkGeneric
03/2007
1Small Interfering RNA (siRNA)IBA
03/2007
1Cytochromes c (Cytochrome c)IBA
03/2007
1BuffersIBA
03/2007
1ReninIBA
02/2006
1Atrial Natriuretic Factor (ANF)IBA
02/2006
1Vasopressins (Vasopressin)IBA
02/2006
1cariporideIBA
12/2005

Therapy/Procedure

1Lasers (Laser)
10/2005